Depression is a common mental disorders with incidence of 15-20% which cause dysfunction in different social and personal aspects of life, and anhedonia and emotional tension.
Rose is probably the first flower which its oil had been extracted in Iran by distillation method in the 10th Christian century.
Rose has been in use for a long time as a hilarity enhancer, anti-depressant and anti-anxiety(4,5,6) and in aromatherapy it is used as a mild but powerful sexual enhancer in men and women and it is a perfect oil for skin care.
Since rose oil has many ideal characteristics, it causes desired relaxation. Rose oil also has shown stimulant effect on human brain.
In a double-blind, placebo-controlled empirical study ; the anti-depressant effect of rose oil on laboratory rat in comparison with placebo ; the rose oil with 10, 20 and 40% concentration reduce depression significantly that is similar to the amphetamine’s effects. The researchers found that since the anti-depressant effect of rose drops appeared acutely and in a short period of time, like amphetamine, it is probable that, it’s effect is due to release of pre-synaptic amines .Of course it should be considered that the assumed mechanism of drug’s effect on animals may not necessarily be the same as the human’s depression’s mechanism.