The results of this study showed that both drugs reduced the symptoms of the disease such as unpleasant fish odor, homogeneous secretion and erythema and edema of the vulva and vagina and clue cells (p = 0.000). In all cases, the response rate to Lecorx vaginal cream was better and even improved erythema, edema of the vulva and vagina significantly better than metronidazole tablets (p = 0.02). Also in a clinical trial; 90 married women aged 18-40 years with bacterial vaginosis were randomly divided into two equal groups and used Lecorx vaginal cream or metronidazole vaginal gel once a night for 5 nights and after 2-7 days the effects of these two drugs on the symptoms. Patients were examined. Diagnostic tools were the use of Amsel criteria and hot staining of discharge smear. Based on the results of this study after treatment; Patients’ symptoms and their Amsel criteria were significantly reduced. Vaginal irritation was reported in 14% of Lecorx vaginal cream users and in 4.5% of metronidazole vaginal gel users. Metronidazole vaginal gel users experienced dizziness (60.8%) and metallic taste sensation (40.5%), but were not reported in Lecorx users. The researchers concluded that the therapeutic effects of Lecorx vaginal cream on bacterial vaginosis are similar to metronidazole vaginal gel, and in cases where the patient is interested in using herbal medicines or has side effects with metronidazole, Lecorx vaginal cream may be a good choice for treating bacterial vaginosis. In an uninformed clinical trial, 140 patients with vaginal trichomoniasis, 140 patients with bacterial vaginosis and 140 patients with concomitant vaginal trichomoniasis and bacterial vaginosis who were referred to the gynecological clinics of Shiraz University of Medical Sciences were studied. . For each woman, a sample was sent to the laboratory for diagnosis of trichomoniasis infection based on positive wet smear and a sample for hot staining for diagnosis of bacterial vaginosis. With a definite diagnosis of trichomoniasis or bacterial vaginosis, or both, the patient was randomly assigned to the relevant experimental or control group. In the experimental groups, patients were given 0.1% Vaginal Thyme vaginal cream (modified Lecorx vaginal cream with modified base) and placebo oral pill for one week.